The Clinch River gorge area of Russell County, Virginia, contains several species of biogeographic interest. At or near the southeastern extent of their ranges are Sullivantia sullivantii, Campanula rotundifolia, Galium boreale, Rhynchospora capillacea, Paxistima canbyi, Apocynum sibiricum, Euphorbia purpurea, Deschampsia caespitosa, and Fraxinus nigra. At or near the northeastern extent are Lithospermum tuberosum and Viola walteri. Several other unusual species occur here. Details of physiography and habitats are given.