The vascular flora of the Jones Ecological Research Center (Ichauway), a remnant longleaf pine/wiregrass ecosystem located in the Coastal Plain of Georgia, was inventoried. High species richness and large numbers of rare and endemic plants are associated with the open, fire-maintained longleaf pine forests and associated depressional wetlands and riparian hardwood forests. The study identified 1,013 taxa in 466 genera and 134 families. The total includes 392 species that are the first record of occurrence for Baker County, Georgia. The Georgia Natural Heritage Program lists 25 of these species as endangered, rare, or of special concern in the state of Georgia, two of which, Lindera melissaefolium and Schwalbea americana, are listed as federally endangered. Ninety-three (9%) of the taxa are introduced.