The vascular flora of Wolf Cove and the surrounding Cumberland Plateau in Franklin County, Tennessee, was sampled during two full growing seasons in 1985 and 1986. Eight hundred twelve collections were made comprising 573 species and lesser taxa in 329 genera and 109 families, including 213 county records. The four largest families were the Asteraceae (90 species), Poaceae (41 species), Cyperaceae (39 species), and Fabaceae (29 species). These four families constitute 34.1% of the flora. Twenty-nine species of exotic plants (5.1% of the flora) were collected. Nine taxa are listed as Threatened or Special Concern in Tennessee: Hieracium scabrum, Hydrastis canadensis, Panax quinquefolius, Synandra hispidula, Talinum mengesii/teretifolium, Trichomanes boschianum, Helianthus eggertii, Polymnia laevigata, and Spiranthes ovalis. Two taxa, Helianthus eggertii and Carex purpurifera, are candidates for federal listing (Category 2). Voucher specimens are on deposit at TENN.