A survey was made of the vascular flora of Little Talbot Island State Park, encompassing the entire island of approximately 2,350 acres (951 ha). The plant communities on this barrier island are influenced dynamically by marine environmental forces and exhibit comparatively little biological diversity. Collections of 289 vascular plant species, representing genera in 89 families, were made from February 1990 to September 1992 and are compiled in an annotated list. Voucher specimens have been placed at FLAS; a second set of vouchers will be distributed at a later time. It is hoped that this list of taxa (and the herbarium specimens) will provide a useful resource for those interested in the flora and ecology of barrier islands.