Epiphyllous liverworts are reported for the first time from North Carolina and Tennessee. The epiphyllous taxa include seven species of liverworts, with Cololejeunea biddlecomiae and Frullania asagrayana reported as epiphylls for the first time. Rhododendron maximum and rarely Leucothoe editorum were host species. Most occurrences, with the exception of those in the escarpment gorge region in South Carolina, consist of a few scattered liverwort shoots on 1-3 Rhododendron leaves. Cololejeunea cardiocarpa, though uncommon, appears specially adapted and successful as an epiphyll in the Southern Appalachians.